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. 2012 Feb 8;7(2):e31060. doi: 10.1371/journal.pone.0031060

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This is an open-access article distributed under the terms of the Creative Commons Public Domain declaration, which stipulates that, once placed in the public domain, this work may be freely reproduced, distributed, transmitted, modified, built upon, or otherwise used by anyone for any lawful purpose.

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(a) Effect on cell invasion: Invasive properties of A-498 cells were decreased after the inhibition of miR-21 as compared to the negative control, Stained A-498 cells (Magnification-40×); Absorbance at 560 nm (p value 0.026). (b) Effect on cell migration: Migratory properties of A-498 cells were also decreased after the inhibition of miR-21 as compared to the negative control, Stained A-498 cells (Magnification-40×); Absorbance at 560 nm (p value 0.016).