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| Compound | Target | EC50 (nM) | CC50 (nM) | ||
| Calcein | Intracellular ATP | Cell # | |||
| HCV-796 | HCV NS5B | 15 | >44,444 | >44,444 | >44,444 |
| Cyclosporine A | Cyclophilin A | 259 | 13,830 | 11,930 | 10,210 |
| 17-AAG | HSP90 | 12 | 21,040* | 38 | 5 |
| Gemcitabine | Ribonucleotide reductase | 12 | >44,444 | 6 | 4 |
| Colchicine | Microtubules | 9 | >44,444* | 16 | ND** |
| Puromycin | Ribosome | 290 | 1,070 | 516 | 52 |
*Non-standard dose-response curve.
**Altered cell morphology interferes with accurate cell number determination.
