Table 1. N, mean age (standard deviation) and percentage of males and ApoE ε3 carriers, in the GOLDN study population by LRP-1 genotype group.
| Genotypes† | P ‡ | |||
| aa | aA | AA | ||
| C766T | ||||
| N | 16 | 246 | 771 | |
| Gender, % male | 31.25 | 45.93 | 48.9 | 0.29 |
| Age, y | 48.83 (14.84) | 49.55 (16.12) | 48.50 (16.24) | 0.68 |
| Current smokers, % | 0 | 7.32 | 7.52 | 0.52 |
| Alcohol intake, g/day | 3.42 (2.69) | 8.08 (29.53) | 5.56 (16.54) | 0.16 |
| I10701 | ||||
| N | 110 | 428 | 493 | |
| Gender, % male | 50.00 | 48.83 | 46.45 | 0.69 |
| Age, y | 49.48 (17.69) | 47.57 (15.94) | 49.65 (16.02) | 0.13 |
| Current smokers, % | 4.55 | 8.18 | 7.30 | 0.43 |
| Alcohol intake, g/day | 4.87 (9.09) | 5.44 (18.41) | 6.97 (23.50) | 0.42 |
| I68477 | ||||
| N | 91 | 456 | 483 | |
| Gender, % male | 48.24 | 47.37 | 47.25 | 0.96 |
| Age, y | 48.33 (15.88) | 49.13 (16.59) | 49.07 (15.51) | 0.73 |
| Current smokers, % | 12.09 | 7.24 | 6.63 | 0.19 |
| Alcohol intake, g/day | 3.24 (8.16) | 6.06 (21.25) | 6.70 (21.05) | 0.33 |
†
a = minor allele; A = major allele.
‡
P-values were derived from tests of null hypothesis that no group is different, using a 1-way ANOVA for continuous traits or the χ2 test for categorical variables.