Table 2.
1H- and 13C-NMR Spectral Assignments (δ/ppm) for Turbostatins 3 and 4 in Py-d5
| Position | δH | δC | ||
|---|---|---|---|---|
| 3 | 4 | 3 | 4 | |
| Lipid Base Unit | ||||
| 1a | 4.81 (m) | 4.82 (m) | 70.44 | 70.45 |
| 1b | 4.24 (m) | 4.23 (m) | ||
| 2 | 4.80 (m) | 4.81 (m) | 55.04 | 55.03 |
| 3 | 4.75 (m) | 4.75 (m) | 72.60 | 72.59 |
| 4 | 5.99 (dd, 6.0, 15.2) | 5.98 (dd, 6.0, 15.0) | 132.15 | 132.18 |
| 5 | 5.85 (dt, 6.0, 15.2) | 5.83 (dt, 6.0, 15.0) | 132.50 | 132.49 |
| 6 | 2.03 (q, 7.2) | 2.01(q, 7.0) | 32.72 | 32.70 |
| 7~15 | 1.21 (brs) | 1.21 (brs) | 22.9~32.1 | 22.9~32.1 |
| 16 | 0.85 (t, 8.6) | 0.85 (t, 8.6) | 14.26 | 14.25 |
| NH | 8.37 (d, 7.7) | 8.36 (d, 7.8) | ||
| N-Acyl Unit | ||||
| 1′ | 173.33 | 173.33 | ||
| 2′ | 2.41 (t, 7.2) | 2.41 (t, 7.1) | 32.71 | 32.70 |
| 3′ | 1.80 (m) | 1.80 (m) | 26.38 | 26.38 |
| 4′~15′ or 17′ | 1.21 (brs) | 1.21 (brs) | 22.9~32.1 | 22.9~32.1 |
| 16′ or 18′ | 0.85 (t, 8.6) | 0.85 (t, 8.6) | 14.26 | 14.25 |
| Glycoside | ||||
| 1″ | 4.89 (d, 7.5) | 4.88 (d, 7.3) | 106.47 | 106.46 |
| 2″ | 4.52 (dd, 7.5, 9.5) | 4.52 (dd, 7.5, 9.4) | 72.71 | 72.71 |
| 3″ | 4.16 (dd, 3.0, 9.5) | 4.14 (dd, 3.0, 9.4) | 75.38 | 75.40 |
| 4″ | 4.56 (d, 3.0) | 4.55 (3.0) | 70.21 | 70.22 |
| 5″ | 4.07 (dd, 6.0, 9.0) | 3.07 (dd, 6.2, 8.9) | 77.07 | 77.06 |
| 6″ | 4.44 (m) | 4.44 (m) | 62.34 | 62.35 |