Table 1.

Demographic, CNS collection and toxicological data on subjects with MDD, BPD and age / sex matched controls used in this study. Drugs in brackets were prescribed within a month of death but not detected in the blood at autopsy.

Case	Diagnosis	Gender	Age	PMI	pH	DOI	Cause of death	Antidepressants	Dose (mg/L)	Mood stabilizers	Dose (mg/L)	Other	Dose (mg/L)
1	Control	Male	42	30.5	6.45		Ischemic heart disease
2	Control	Male	52	33.75	6.52		Cardiomegaly; IHD/CAD
3	Control	Female	47	24	5.89		Pulmonary embolus
4	Control	Female	75	53	6.01		Multiple organ failure; Septicaemia
5	Control	Male	70	59	6.11		RV Rupture following pericardial drainage
6	Control	Male	75	69.4	6.19		Cardiogenic shock
7	Control	Male	55	30.5	6.69		Coronary artery atherosclerosis
8	Control	Male	66	71.75	6.47		Coronary artery atheroma
9	Control	Female	80	55	6.28		Ischemic heart disease
10	Control	Female	63	50.25	6.55		Coronary artery atherosclerosis
11	MDD	Male	37	57.75	6.84	14	Hanging	Sertraline	0.2			Ethanol	Detected
12	MDD	Male	51	41	6.71	15	Hanging	Clomipramine Desmethyclomipramine	0.3 Detected
13	MDD	Female	50	50.5	6.85	40	Mixed drug toxicity					Diazepmam Nordiazepam Codeine Paracetamol Propoxyphene Norpropoxyphene Metoclopramide Verapamil Zolpidem Tramadol	~0.8 ~1.5 0.1 ~220 7.4 27 ~53 ~3.5 ~0.1 ~15.2
14	MDD	Female	77	16.7	6.49	26	Doxepin toxicity		Doxepin	5.4
15	MDD	Male	69	44.5	6.45	20	Drowning					Diphenhydramine	~4
16	MDD	Male	79	24	6.32	17	CO poisoning		Nortriptyline	~0.7		Nordiazepam Paracetamol	~0.1 ~1000
17	MDD	Male	55	47.75	6.60	3	Hanging		Venlafaxine	~0.2
18	MDD	Male	68	60.75	6.65	9	Hanging		Citalopram Mianaserin	Trace ~0.1		Temazepam	~0.2
19	MDD	Female	87	24.5	6.44	7	Chest infection		(Setraline)
20	MDD	Female	51	23.5	6.49	25	Toxicity to Quetiapine		(Mirtazapine)			Diazepam Nordiazepam Quetiapine	100 ~0.4 ~0.3
21	BPD	Male	38	24	6.42	8	CO poisoning					Ethanol Codeine Paracetamol Doxylamine	Detected 0.3 46 0.2
22	BPD	Male	59	34	6.46	24	Ruptured aorta
23	BPD	Female	42	25	6.54	20	Hanging	Venlafaxine	~0.5	(Lithium)		Ethanol Diazepam	Detected ~0.1
24	BPD	Female	64	26	6.46	8	IHD/CAD	(Venlafaxine)		(Na Valproate)
25	BPD	Male	66	17	6.41	12	Aspirated on food
26	BPD	Male	79	8.25	6.09	17	Cholecystitis in association with cardiomegaly			Na Valproate	16	Zolpidem	0.2mg
27	BPD	Male	59	37.5	5.97	8	Ischemic heart disease; Coronary artery atherosclerosis			(Lithium)
28	BPD	Male	61	58	6.44	40	Acute myocardial infarction			(Na Valproate)
29	BPD	Female	74	45	6.26	35	Combined drug toxicity	Amitriptyline Nortriptyline Dothiepin	4.9 3.1 4.0	Na Valproate	10
30	BPD	Female	56	86	6.43	N/A	CO poisoning	Venlafaxine	~0.6	Carbamazepine	~1.8	Ethanol Paracetamol	Detected Trace