Table 4.
Symptoms and exposures according to family type (includes affected individuals in the non-familial group and all individuals in the duplex and multiplex kindreds)
| Nonfamilial | Duplex | Multiplex | p-value | |
|---|---|---|---|---|
| BE/EAC/EGJAC | ||||
| Affected | 830 | 421 | 146 | |
| Unaffected | N/A | 3071 | 1065 | |
| Total | 830 | 3438 | 1211 | |
|
| ||||
| Heartburn Present | ||||
| Yes | 507/724(70.03%) | 339/528(64.20%) | 178/263(67.68%) | 0.2294* |
| No | 211/724(29.14%) | 183/528(34.66%) | 84/263(31.94%) | |
| Unknown | 6/724(0.83%) | 6/528(1.14%) | 1/263(0.38%) | |
|
| ||||
| Regurgitation Present | ||||
| Yes | 475/717(66.25%) | 301/525(57.33%) | 144/264(54.55%) | 0.0014* |
| No | 233/717(32.50%) | 216/525(41.14%) | 118/264(44.70%) | |
| Unknown | 9/717(1.26%) | 8/525(1.52%) | 2/264(0.76%) | |
|
| ||||
| Smoking | ||||
| Yes | 466/725(64.28%) | 271/529(51.23%) | 120/263(45.63%) | 6.3E-8* |
| No | 251/725(34.62%) | 253/529(47.83%) | 140/263(53.23%) | |
| Unknown | 8/725(1.10%) | 5/529(0.95%) | 3/263(1.14%) | |
|
| ||||
| Alcohol | ||||
| Yes | 581/723(80.36%) | 446/527(84.63%) | 238/261(91.19%) | 8.2E-4* |
| No | 126/723(17.43%) | 74/527(14.04%) | 22/261(8.43%) | |
| Unknown | 16/723(2.21%) | 7/527(1.33%) | 1/261(0.38%) | |
|
| ||||
| Average BMI | 29.6 | 28.9 | 28.6 | 0.0033# |
#
Wilcoxon test p-value;
*
Fishers exact test p-value;
^
Chi-square test p-value