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. Author manuscript; available in PMC: 2013 Feb 27.
Published in final edited form as: Transplantation. 2012 Feb 27;93(4):373–382. doi: 10.1097/TP.0b013e3182419829

Figure 1.

Figure 1

Overexpression of A20 decreases neointima formation in aorta to carotid allografts. A. Representative photomicrographs of hematoxylin-eosin stained whole and partial vessel cross-sections of allografted vessels 4 weeks after transplantation show lesions of TA. B. Morphometric analysis of intima/media (I/M) ratios demonstrates a significant decrease in neointima formation in rAd.A20-treated allografts, as compared to saline and rAd.βgal controls. 6-10 sections per vessel were measured using Image J. Results represent mean±SE of 5 to 6 mice per group. C. Overexpression of A20 in the grafts was confirmed by immunostaining (IS) that showed A20 expression in EC and the two first layers of medial SMC of the allograft five days after transduction. I-intima, M-media, original magnification X400. *p<0.05.