Skip to main content
. Author manuscript; available in PMC: 2013 Feb 8.
Published in final edited form as: J Am Chem Soc. 2012 Jan 26;134(5):2681–2690. doi: 10.1021/ja209959t

Figure 2.

Figure 2

ITC Study of Heparin-NP Interaction. Heparin (0.1 mM) in 10 mM PBS was titrated into 1mg/mL of a) NP–1 (10% BIS, 90% AAm); b) NP–2 (5% AAc); c) NP–3 (2% ATC); d) NP–4 (5%ATC); e) NP–6 (2% APM);f) NP–8 (5% IM). For each titration, the upper graph shows the titration curve. In most cases, heat is generated upon injection of the ligand into the cell. The titration curve was integrated in the lower graph and fitted by a single-site model.