Fig. 6.

Dual immunostained fibrillin-2 and fibrillin-1 in the NP. Typical dual immunostained image of a section showing organisation of fibrillin-2 (green: A), fibrillin-1 (red: B), and the merged image (C) with DAPI staining of the nucleus (blue). The images show that fibrillin-2 is organised not only around the cells (white arrows in A) but also is extensively distributed in the inter-territorial matrix (yellow arrows in A) where little/filamentous fibrillin-1 is present. (D) Merged image of fibrillin-1 and -2 at a higher magnification, showing a network of fibrillin-1, and -2 forming a chondron-like structure around the cell.