Table 2.

Bins attaining suggestive significance (P ≤ 0.05) in weighted analyses^a

Phenotype; bin	Chromosomal location	Average rank		P-value for low heterogeneity
		Observed	P-value
eGFR
9.1	9p24.3–9p22.3	84	0.0052	0.4145
7.2	7p15.3–7p13	83	0.0062	0.6830
16.3	16q12.2–16q23.1	82	0.0072	0.5705
13.4	13q33.1–13q34	78	0.0250	0.6052
14.3	14q23.3–14q32.12	77	0.0298	0.5067
7.4	7q11.23–7q22.3	76	0.0401	0.2298
Serum creatinine
9.6	9q34.11–9q34.3	88	0.0017	0.4266
7.3	7p13–7q11.23	86	0.0029	0.8663
16.4	16q23.1–16q24.1	81	0.0119	0.8982
9.4	9q21.32–9q31.2	80	0.0151	0.7710
10.3	10p11.23–10q22.1	79	0.0185	0.5645
9.5	9q31.2–9q34.11	78	0.0278	0.4132
9.2	9p22.3–9p21.1	78	0.0306	0.9721
9.3	9p21.1–9q21.32	78	0.0308	0.9793
11.4	11q13.3–11q22.1	77	0.0376	0.8685
11.3	11p12–11q13.3	76	0.0452	0.7713
Creatinine clearance
7.3	7p13–7q11.23	93	0.0195	0.6463
6.6	6q25.3–6q27	91	0.0310	0.5524
16.4	16q23.1–16q24.1	91	0.0315	0.6064
10.4	10q22.1–10q23.32	90	0.0337	0.9859
2.6	2q21.1–2q24.1	88	0.0409	0.7208
ACR
10.4	10q22.1–10q23.32	82	0.0145	0.9425
7.5	7q22.3–7q34	82	0.0154	0.3294
3.6	3q21.2–3q25.32	81	0.0190	0.3643
7.4	7q11.23–7q22.3	81	0.0205	0.5862
1.2	1p36.21–1p35.2	79	0.0305	0.1693

^aGFR, glomerular filtration rate. The threshold for genome-wide significance would be P-value ≤0.05/120 = 0.00042. No bin attained this level in the main analysis.