Table 3.

Observed results from genome scans with LOD scores >3.0^a

	Author	Study	Phenotype	Type of population	Ethnicity	Genomic Location (cM)	LOD Score	GSMA Bin
Chr 1	Schelling [29]	FIND	GFR	Diabetic	Mexican-American	259	3.78	1.9
Chr 2	Freedman [33]	DHS	GFR	Diabetic/hypertensive	African-American and Caucasian	77	4.45	2.3
	Schelling [29]	FIND	GFR	Diabetic	Mexican-American	82	3.02	2.4
	Freedman [33]	DHS	Serum creatinine	Diabetic/hypertensive	African-American and Caucasian	80	3.55	2.3
	Hunt [26]	Utah	Serum Creatinine	General population	European-American	145	3.15	2.6
	Freedmanb [36]		All-cause ESRD	CKD	African-American	186	3.05	2.7
	Plachac [37]	Joslin	Cystatin	Diabetic	European-American	202	4.1	2.8
Chr 3	Freedmanb [36]		All-cause ESRD	CKD	African-American	7	3.18	3.3
Chr 5	Krolewski [30]	Joslin	ACR	Diabetic	European-American	69	3.4	5.3
Chr 6	Freedmanb [36]		All-causeESRD	CKD	African-American	162.5	5.72	6.6
Chr 7	Turner [35]	GENOA	GFR	Hypertensive	African-American	43	3.65	7.2
	Schelling [29]	FIND	GFR	Diabetic	Multiethnic	170	3.28	7.6
	Schelling [29]	FIND	GFR	Diabetic	Mexican-American	170	4.23	7.6
	Plachac [37]	Joslin	Cystatin	Diabetic	European-American	23	4	7.1
Chr 8	Schelling [29]	FIND	GFR	Diabetic	Mexican-American	93	3.95	8.4
Chr 9	Arar [23]	SAFHS	GFR	Hypertensive	Mexican-American	75	3.87	9.3
Chr 10	Placha . [37]	Joslin	Cystatin	Diabetic	European-American	114	3.6	10.4
Chr 12	Mottl [24]	SHFS	GFR	General population	American Indian (Arizona)d	39	3.5	12.2
Chr 13	Freedmanb [36]		All-cause ESRD	CKD	African-American	91	4.94	13.4
Chr 14	Leon [34]	HyperGEN	GFR	Hypertensive	African-American and Caucasian	94	3.29	14.3
Chr 15	Leon [34]	HyperGEN	GFR	Hypertensive	African-American and Caucasian	16	3.13	15.1
Chr 22	Krolewski [30]	Joslin	ACR	Diabetic	European-American	33	3.4	22.2
	Pattaro [27]	Eurospan	Serum creatinine	General population	European-American (MICROS)d	61	3.4	22.2

^aDHS, Diabetes Heart Study; GFR; estimated glomerular filtration rate; FIND, Family Investigation of Nephropathy and Diabetes; GENOA, Genetic Epidemiology Network of Arteriopathy; HyperGEN, Hypertension Genetic Epidemiology Network Study; SAFHS, San Antonio Family Heart Study; SHFS, Strong Heart Family Study.

^bStudies with dichotomous outcomes, not included in present analysis.

^cNot analyzed as part of study.

^dSubgroup in study.