Table 1.
Volumes of interest analysis of relative metabolic activity during the Simon task (TR) and control tasks (TC and TI).
| Brain area | TR versus TN | TC versus TN | TI versus TN | TI versus TC |
|---|---|---|---|---|
| Rostral anterior cingulate cortex (Cg1)1 | l: 99.7 | l: 98.9 | l: 96.3 | l: 97.4 |
| r: 98.6 | r: 99.5 | r: 102.3 | r: 102.9 | |
| Rostral anterior cingulate cortex (Cg2)1 | l: 104.8 | l: 98.4 | l: 98.3 | l: 99.9 |
| r: 97.4 | r: 97.9 | r: 98.8 | r: 101.2 | |
| Frontal association cortex (FrA) | l: 107.1 | l: 101.7 | l: 104.4 | l: 104.1 |
| r: 108.9 | r: 102.4 | r: 100.9 | r: 103.5 | |
| Orbitofrontal cortex (OFC) | l: 100.4 | l: 99.4 | l: 97.2 | l: 97.8 |
| r: 100.4 | r: 100.1 | r: 103.3 | r: 103.1 | |
| Prelimbic cortex | l: 100.7 | l: 97.0 | l: 96.9 | l: 99.9 |
| r: 106.5; p = 0.0006 | r: 103.4 | r: 102.7 | r: 99.9 | |
| Anterior motor cortex (aM1)1 | l: 101.5 | l: 98.0 | l: 103.3 | l: 106.7 |
| r: 102.1 | r: 94.6 | r: 94.8; p = 0.0440 | r: 100.5 | |
| Posterior motor cortex (pM1)2 | l: 98.9 | l: 98.1 | l: 102.3 | l: 104.3 |
| r: 101.1 | r: 99.0 | r: 98.7 | r: 99.9 | |
| Anterior premotor cortex (aM2)1 | l: 103.3 | l: 98.6 | l: 101.1 | l: 102.8 |
| r: 103.3 | r: 99.4 | r: 99.9 | r: 100.5 | |
| Posterior premotor cortex (pM2)2 | l: 96.4 | l: 92.9; p = 0.0251 | l: 95.0 | l: 102.2 |
| r: 100.8 | r: 101.2 | r: 101.0 | r: 100.0 | |
| Posterior parietal cortex | l: 96.5 | l: 97.0 | l: 98.5 | l: 101.6 |
| r: 98.0 | r: 97.1 | r: 98.7 | r: 102.3 | |
| Hippocampus | l: 102.1 | l: 100.8 | l: 99.3 | l: 98.5 |
| r: 101.5 | r: 100.3 | r: 103.0 | r: 102.7 | |
| Amygdala | l: 108.5 | l: 106.2 | l: 103.7 | l: 97.8 |
| r: 98.0 | r: 97.8 | r: 104.0 | r: 106.9 | |
| Dorsomedial striatum | l: 100.2 | l: 101.4 | l: 97.4 | l: 96.1 |
| r: 101.3 | r: 101.3 | r: 105.7; p = 0.0041 | r: 104.4 | |
| Dorsolateral striatum | l: 99.5 | l: 100.0 | l: 99.6 | l: 99.5 |
| r: 100.2 | r: 97.9 | r: 102.9 | r: 105.1; p = 0.0006 | |
| Lateral septum | l: 100.0 | l: 102.4 | l: 94.6 | l: 92.4 |
| r: 101.0 | r: 96.3 | r: 94.3 | r: 97.9 | |
| Medial septum plus diagonal band of Broca | l: 92.0 | l: 91.1 | l: 93.2 | l: 103.1 |
| r: 94.0 | r: 93.4 | r: 93.2 | r: 100.7 | |
| Caudoventral auditory cortex (Te3V) | l: 116.6 | l: 104.6 | l: 117.6: p = 0.0180 | l: 111.6 |
| r: 118.5 | r: 106.7 | r: 109.2 | r: 105.6 |
1Up to 0.6 mm rostral from Bregma.
2From 0.6 mm rostral to 2.0 mm caudal from Bregma.
Given values represent % regional metabolic activity in the PET sessions TR (50% incompatible and 50% compatible trials in randomized order), TC (compatible trials only), and TI (incompatible trials only) with respect to TN (neutral trials only; column 2–4) or TC (column 5). Underlined are values significantly different from 100%, i.e., from values in TN (column 2–4) or TC (column 5). Shown are p-values uncorrected for multiple testing. l, Left hemisphere; r, right hemisphere.