Table 2.

Multivariable logistic regression analysis of association between biopsy Gleason score and adverse pathology in patients with biopsy Gleason sum 7–10 tumors in the SEARCH Database

	Odds Ratio	95% CI	p value
4+3 vs. 3+4
Positive surgical margins	1.63	0.92 – 2.89	0.09
Extracapsular extension	2.16	1.18 – 3.94	0.01
Seminal vesicle invasion	6.43	2.76 – 14.98	<0.001
≥4+4 vs. 4+3
Positive surgical margins	0.87	0.45 – 1.69	0.69
Extracapsular extension	0.78	0.40 – 1.54	0.48
Seminal vesicle invasion	0.61	0.28 – 1.29	0.19