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Expression of HIV-1 gag/pol mRNA in mononuclear cells induced by MTB is inhibited by IM. Mononuclear cells were stimulated with MTB H37RvL (1 μg/ml) in the presence or absence of IM, or left unstimulated (–). HIV-1 gag/pol mRNA was assessed at 24 h. (A) Results from PFMCs obtained from eight HIV/TB patients are shown. (B) Data for adherent MN from HIV-1 singly infected subjects (n=5) are shown.
