Table 4.
Human epidermal growth factor receptor 2 (HER2)-neu and labelling index according to age. Younger age correlates with HER2-neu positive status and high Ki67.
| HER2 status | |||||
| ≤35 (%) | 36–40 (%) | 41–45 (%) | 46–50(%) | Total (%) | |
|
| |||||
| HER2 0 | 14 (35.9) | 31 (34.4) | 52 (36.9) | 100 (44.6) | 197 (39.9) |
| HER2 1+ | 6 (15.4) | 18 (20.0) | 28 (19.9) | 42 (18.8) | 94 (19.0) |
| HER2 2+ | 6 (15.4) | 16 (17.8) | 28 (19.9) | 45 (20.1) | 95 (19.2) |
| HER2 3+ | 13 (33.3) | 25 (27.8) | 33 (23.4) | 37 (16.5) | 108 (21.9) |
| Missing | 518 | ||||
|
| |||||
| Labelling index—Ki 67 | |||||
| Ki67 ≤10% | 5 (8.1) | 28 (23.1) | 56 (24.2) | 99 (27.3) | 188 (24.2) |
| Ki67 >10%* | 57 (91.9) | 93 (76.9) | 175 (75.8) | 264 (72.7) | 589 (75.8) |
| Missing | 235 | ||||
*χ 2 = 9.53; P = .002.