Skip to main content
. 2011 Sep 1;1(4):263–281. doi: 10.1534/g3.111.000422

Table 1 . Correlations between fermentation phenotypes and gene expression.

Name Correlation P Adjusted P Function
Spearman correlations relative to Rmax
 MEP2 0.7456 2.27E−06 0.002 Ammonium permease involved in regulation of pseudohyphal growth
 MAE1 0.6902 2.44E−05 0.01 Mitochondrial malic enzyme
 PUT1 0.6833 3.16E−05 0.01 Proline oxidase
 SNG1 0.6824 3.28E−05 0.01 Protein involved in nitrosoguanidine (MNNG) resistance
 SUP35 0.6795 3.64E−05 0.01 Translation termination factor eRF3
 YLR410W-B 0.6598 7.30E−05 0.013 Retrotransposon TYA Gag and TYB Pol genes
 YGR038C-B 0.6452 1.18E−04 0.017 Retrotransposon TYA Gag and TYB Pol genes
 YFL002W-A 0.6357 1.60E−04 0.018 Retrotransposon TYA Gag and TYB Pol genes
 YBR016W 0.6272 2.08E−04 0.02 Plasma membrane protein of unknown function
 YPR137C-B 0.6241 2.28E−04 0.02 Retrotransposon TYA Gag and TYB Pol genes
 YCL076W 0.6239 2.30E−04 0.02 Dubious open reading frame unlikely to encode a protein
 YLR035C-A 0.6208 2.52E−04 0.022 Retrotransposon TYA Gag and TYB Pol genes
 RPN6 0.6117 3.29E−04 0.025 Essential
 YML131W 0.6094 3.51E−04 0.026 Putative protein of unknown function with similarity to medium chain dehydrogenase/reductases
 YDR261W-B 0.6038 4.11E−04 0.029 Retrotransposon TYA Gag and TYB Pol genes
 YBL113C −0.7505 1.79E−06 0.002 Helicase-like protein encoded within the telomeric Y element
 YHR219W −0.7487 1.95E−06 0.002 Putative protein of unknown function with similarity to helicases
 YKL050C −0.7429 2.58E−06 0.002 Protein of unknown function
 YHR097C −0.7414 2.78E−06 0.002 Putative protein of unknown function
 YLR326W −0.7409 2.84E−06 0.002 Putative protein of unknown function
 YRF1-3 −0.7209 7.01E−06 0.004 Helicase encoded by the Y element of subtelomeric regions
 YOR289W −0.716 8.64E−06 0.005 Putative protein of unknown function
 YJL225C −0.6931 2.18E−05 0.01 Putative protein of unknown function
 GFD1 −0.6902 2.44E−05 0.01 Coiled-coiled protein of unknown function
 APM1 −0.6864 2.82E−05 0.01 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)
 PHM7 −0.6848 2.99E−05 0.01 Protein of unknown function
 YMR244C-A −0.6775 3.91E−05 0.01 Putative protein of unknown function
 MSC3 −0.6742 4.42E−05 0.011 Protein of unknown function
 MSO1 −0.6713 4.90E−05 0.011 Probable component of the secretory vesicle docking complex
 TMA23 −0.671 4.94E−05 0.011 Nucleolar protein of unknown function implicated in ribosome biogenesis
 MRS1 −0.6693 5.26E−05 0.011 Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1)
 CUP1-2 −0.6659 5.91E−05 0.012 Metallothionein
 BNA1 −0.6591 7.47E−05 0.013 3-hydroxyanthranilic acid dioxygenase
 IES5 −0.6589 7.53E−05 0.013 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
 VOA1 −0.6515 9.65E−05 0.015 Putative protein of unknown function
 NSA1 −0.6512 9.72E−05 0.015 Constituent of 66S pre-ribosomal particles
 YGR251W −0.6486 1.06E−04 0.016 Essential protein required for maturation of 18S rRNA
 CUP1-1 −0.6475 1.10E−04 0.016 Metallothionein
 YPL080C −0.6437 1.24E−04 0.017 Dubious open reading frame unlikely to encode a protein
 PIN2 −0.6419 1.32E−04 0.017 Protein that induces appearance of [PIN+] prion when overproduced
 BSC4 −0.6406 1.37E−04 0.017 Protein of unknown function
 CSM2 −0.6397 1.41E−04 0.017 Protein required for accurate chromosome segregation during meiosis
 YMR086W −0.6392 1.43E−04 0.017 Protein of unknown function that may interact with ribosomes
 YEL077C −0.6386 1.46E−04 0.017 Helicase-like protein encoded within the telomeric Y element
 COX16 −0.6357 1.60E−04 0.018 Mitochondrial inner membrane protein
 YLL066C −0.6352 1.62E−04 0.018 Putative protein of unknown function with similarity to helicases
 OXR1 −0.6348 1.64E−04 0.018 Protein of unknown function required for normal levels of resistance to oxidative damage
 YRF1-6 −0.6328 1.75E−04 0.018 Helicase encoded by the Y element of subtelomeric regions
 YML133C −0.629 1.97E−04 0.02 Putative protein of unknown function with similarity to helicases
 DAL81 −0.6285 2.00E−04 0.02 Positive regulator of genes in multiple nitrogen degradation pathways
 TOA1 −0.6268 2.11E−04 0.02 TFIIA large subunit
 MDM12 −0.6254 2.19E−04 0.02 Mitochondrial outer membrane protein
 CDC12 −0.6248 2.24E−04 0.02 Component of the septin ring of the mother-bud neck that is required for cytokinesis
 YMR306C-A −0.619 2.66E−04 0.022 Dubious open reading frame unlikely to encode a functional protein
 VPS24 −0.6174 2.78E−04 0.023 One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III)
 DDC1 −0.6154 2.95E−04 0.024 DNA damage checkpoint protein
 ATH1 −0.6139 3.09E−04 0.025 Acid trehalase required for utilization of extracellular trehalose
 KES1 −0.6127 3.19E−04 0.025 Member of the oxysterol binding protein family
 MEC3 −0.611 3.36E−04 0.025 DNA damage and meiotic pachytene checkpoint protein
 PUP1 −0.6075 3.71E−04 0.027 Endopeptidase with trypsin-like activity that cleaves after basic residues
 YDL173W −0.6038 4.11E−04 0.029 Putative protein of unknown function
 SPG1 −0.6028 4.23E−04 0.03 Protein required for survival at high temperature during stationary phase
Spearman correlations relative to R50
 THI3 0.7442 5.30E−06 0.003 Probable alpha-ketoisocaproate decarboxylase
 THI4 0.7228 1.18E−05 0.006 Thiazole synthase
 ACT1 0.7201 1.31E−05 0.006 Actin
 SCW4 0.7152 1.57E−05 0.006 Cell wall protein with similarity to glucanases
 YLR444C 0.7063 2.19E−05 0.007 Dubious open reading frame unlikely to encode a functional protein
 HPA3 0.7032 2.45E−05 0.007 D-Amino acid N-acetyltransferase
 SNG1 0.6866 2.79E−05 0.007 Protein involved in nitrosoguanidine (MNNG) resistance
 TIM21 0.6845 4.75E−05 0.01 Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex)
 PRE1 0.6783 5.87E−05 0.011 Beta 4 subunit of the 20S proteasome
 PET18 0.6747 6.61E−05 0.012 Protein required for respiratory growth and stability of the mitochondrial genome
 MAP1 0.6556 1.22E−04 0.018 Methionine aminopeptidase
 MAE1 0.6534 1.31E−04 0.018 Mitochondrial malic enzyme
 MEP2 0.6525 1.34E−04 0.018 Ammonium permease involved in regulation of pseudohyphal growth
 YNR048W 0.6463 1.62E−04 0.021 Protein proposed to interact with phospholipid translocases
 ERG20 0.6449 1.69E−04 0.021 Farnesyl pyrophosphate synthetase
 LYS9 0.6387 2.03E−04 0.024 Saccharopine dehydrogenase (NADP+)
 TPK1 0.6356 2.22E−04 0.025 cAMP-dependent protein kinase catalytic subunit
 YAR069C 0.6343 2.31E−04 0.025 Dubious open reading frame unlikely to encode a protein
 BUD31 0.6343 2.31E−04 0.025 Protein involved in bud-site selection
 ARC1 0.6307 2.56E−04 0.025 Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p)
 PAU1 0.6294 2.65E−04 0.025 Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions
 YLR179C 0.6294 2.65E−04 0.025 Protein of unknown function
 CDC45 0.6249 3.01E−04 0.027 DNA replication initiation factor
 RPS21A 0.6236 3.12E−04 0.027 Protein component of the small (40S) ribosomal subunit
 SOL2 0.6218 3.28E−04 0.028 Protein with a possible role in tRNA export
 SSZ1 0.6151 3.93E−04 0.032 Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit
 CDC7 0.6036 5.35E−04 0.038 DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p
 DRN1 0.6031 5.41E−04 0.038 Putative debranching enzyme associated ribonuclease
 JSN1 0.6013 5.66E−04 0.04 Member of the Puf family of RNA-binding proteins
 TVP23 −0.7913 1.42E−06 0.002 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p
 SPC1 −0.7878 1.51E−06 0.002 Subunit of the signal peptidase complex (SPC)
 GCN3 −0.7709 2.21E−06 0.002 Alpha subunit of the translation initiation factor eIF2B
 CUP1-2 −0.7677 2.42E−06 0.002 Metallothionein
 YLL032C −0.7602 3.04E−06 0.002 Protein of unknown function that may interact with ribosomes
 HSP30 −0.7595 1.14E−06 0.002 Hydrophobic plasma membrane localized
 CUP1-1 −0.7179 1.42E−05 0.006 Metallothionein
 APM1 −0.7126 1.74E−05 0.006 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)
 Q0182 −0.7006 2.70E−05 0.007 Dubious open reading frame unlikely to encode a protein
 HSP12 −0.6988 2.88E−05 0.007 Plasma membrane localized protein that protects membranes from desiccation
 ATG1 −0.693 3.54E−05 0.008 Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway
 GND2 −0.693 3.54E−05 0.008 6-phosphogluconate dehydrogenase (decarboxylating)
 ATC1 −0.6814 5.28E−05 0.011 Nuclear protein
 YGR026W −0.6814 5.28E−05 0.011 Putative protein of unknown function
 YEL077C −0.6756 6.41E−05 0.012 Helicase-like protein encoded within the telomeric Y element
 CRS5 −0.6659 8.83E−05 0.014 Copper-binding metallothionein
 RHO5 −0.6641 9.35E−05 0.015 Nonessential small GTPase of the Rho/Rac subfamily of Ras-like proteins
 SPG1 −0.659 7.49E−05 0.013 Protein required for survival at high temperature during stationary phase
 SPS100 −0.6512 1.40E−04 0.019 Protein required for spore wall maturation
 YOR277C −0.6412 1.34E−04 0.018 Dubious open reading frame unlikely to encode a protein
 YOL014W −0.6409 1.90E−04 0.023 Putative protein of unknown function
 SSA4 −0.6343 2.31E−04 0.025 Heat shock protein that is highly induced upon stress
 ADA2 −0.632 2.46E−04 0.025 Transcription coactivator
 PIB2 −0.6298 2.62E−04 0.025 Protein binding phosphatidylinositol 3-phosphate
 YNR047W −0.6249 3.01E−04 0.027 Putative protein kinase that
 INP53 −0.6249 3.01E−04 0.027 Polyphosphatidylinositol phosphatase
 YPC1 −0.6218 3.28E−04 0.028 Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity
 YJL114W −0.6165 3.79E−04 0.031 Retrotransposon TYA Gag gene cotranscribed with TYB Pol
 HXT8 −0.6102 4.49E−04 0.035 Protein of unknown function with similarity to hexose transporter family members
 CYC1 −0.6085 4.70E−04 0.036 Cytochrome c
 CTT1 −0.6067 4.93E−04 0.037 Cytosolic catalase T
 ATP6 −0.605 3.98E−04 0.032 Mitochondrially encoded subunit a of the F0 sector of mitochondrial F1F0 ATP synthase
 FCP1 −0.6049 5.16E−04 0.038 Carboxy-terminal domain (CTD) phosphatase
Spearman correlations relative to R70
 THI3 0.8427 5.18E−09 0 Probable alpha-ketoisocaproate decarboxylase
 YLR444C 0.8028 9.39E−08 0 Dubious open reading frame unlikely to encode a functional protein
 THI4 0.7817 3.40E−07 0 Thiazole synthase
 RPS21A 0.7759 4.71E−07 0 Protein component of the small (40S) ribosomal subunit
 PET18 0.7483 1.99E−06 0.001 Protein required for respiratory growth and stability of the mitochondrial genome
 TPK1 0.7468 2.14E−06 0.001 cAMP-dependent protein kinase catalytic subunit
 SCW4 0.7452 2.31E−06 0.001 Cell wall protein with similarity to glucanases
 ACT1 0.741 2.83E−06 0.001 Actin
 HPA3 0.7243 6.04E−06 0.001 D-Amino acid N-acetyltransferase
 ERG20 0.7227 6.47E−06 0.001 Farnesyl pyrophosphate synthetase
 TIM21 0.7165 8.45E−06 0.001 Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex)
 DRN1 0.7112 1.06E−05 0.001 Putative debranching enzyme associated ribonuclease
 PRE1 0.7109 1.07E−05 0.001 Beta 4 subunit of the 20S proteasome
 YAR069C 0.6963 1.93E−05 0.002 Dubious open reading frame unlikely to encode a protein
 ARR1 0.6951 2.02E−05 0.002 Transcriptional activator of the basic leucine zipper (bZIP) family
 RPL14B 0.694 2.10E−05 0.002 Protein component of the large (60S) ribosomal subunit
 CCT7 0.6931 2.18E−05 0.002 Subunit of the cytosolic chaperonin Cct ring complex
 MAP1 0.6931 2.18E−05 0.002 Methionine aminopeptidase
 RPL14A 0.6916 2.31E−05 0.002 N-terminally acetylated protein component of the large (60S) ribosomal subunit
 CDC7 0.6871 2.74E−05 0.003 DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p
 BUD31 0.6862 2.83E−05 0.003 Protein involved in bud-site selection
 LYS9 0.6851 2.95E−05 0.003 Saccharopine dehydrogenase (NADP+)
 PDC5 0.6836 3.13E−05 0.003 Minor isoform of pyruvate decarboxylase
 YLR179C 0.6836 3.13E−05 0.003 Protein of unknown function
 SSZ1 0.6785 3.78E−05 0.003 Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit
 CTS1 0.6707 5.00E−05 0.004 Endochitinase
 YHB1 0.6575 7.87E−05 0.006 Nitric oxide oxidoreductase
 HTA1 0.6569 8.05E−05 0.006 Histone H2A
 POL30 0.6551 8.55E−05 0.006 Proliferating cell nuclear antigen (PCNA)
 STR3 0.6547 8.68E−05 0.006 Cystathionine beta-lyase
 VPS66 0.6493 1.04E−04 0.007 Cytoplasmic protein of unknown function involved in vacuolar protein sorting.
 RPS10A 0.6455 1.17E−04 0.008 Protein component of the small (40S) ribosomal subunit
 CYS4 0.6429 1.28E−04 0.008 Cystathionine beta-synthase
 ARC19 0.6391 1.44E−04 0.009 Subunit of the ARP2/3 complex
 HYP2 0.6375 1.51E−04 0.009 Translation initiation factor eIF-5A
 RPL25 0.6373 1.52E−04 0.009 Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit
 YNR048W 0.6326 1.76E−04 0.01 Protein proposed to interact with phospholipid translocases
 CHO2 0.6315 1.82E−04 0.01 Phosphatidylethanolamine methyltransferase (PEMT)
 THI21 0.6271 2.09E−04 0.011 Hydroxymethylpyrimidine phosphate kinase
 RSC58 0.6242 2.27E−04 0.012 Component of the RSC chromatin remodeling complex
 GFA1 0.6228 2.37E−04 0.012 Glutamine-fructose-6-phosphate amidotransferase
 GEA1 0.619 2.65E−04 0.014 Guanine nucleotide exchange factor for ADP ribosylation factors (ARF)
 SMF3 0.6177 2.76E−04 0.014 Putative divalent metal ion transporter involved in iron homeostasis
 ZEO1 0.6153 2.96E−04 0.015 Peripheral membrane protein of the plasma membrane that interacts with Mid2p
 DAL7 0.6128 3.18E−04 0.015 Malate synthase
 ADH7 0.6117 3.29E−04 0.016 NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity
 LYS12 0.6095 3.50E−04 0.016 Homo-isocitrate dehydrogenase
 JSN1 0.6075 3.71E−04 0.017 Member of the Puf family of RNA-binding proteins
 YOX1 0.605 3.97E−04 0.018 Homeodomain-containing transcriptional repressor
 CTA1 0.6046 4.02E−04 0.018 Catalase A
 SPC1 −0.8714 3.72E−10 0 Subunit of the signal peptidase complex (SPC)
 HSP30 −0.8505 2.66E−09 0 Hydrophobic plasma membrane localized
 GCN3 −0.844 4.64E−09 0 Alpha subunit of the translation initiation factor eIF2B
 TVP23 −0.824 2.21E−08 0 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p
 HSP12 −0.8238 2.24E−08 0 Plasma membrane localized protein that protects membranes from desiccation
 ATG1 −0.8129 4.84E−08 0 Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway
 GND2 −0.8033 9.13E−08 0 6-phosphogluconate dehydrogenase (decarboxylating)
 SPS100 −0.7748 5.01E−07 0 Protein required for spore wall maturation
 CRS5 −0.7639 9.03E−07 0 Copper-binding metallothionein
 CUP1-2 −0.7632 9.35E−07 0 Metallothionein
 Q0182 −0.7597 1.12E−06 0 Dubious open reading frame unlikely to encode a protein
 CTT1 −0.7352 3.70E−06 0.001 Cytosolic catalase T
 YLL032C −0.7308 4.53E−06 0.001 Protein of unknown function that may interact with ribosomes
 MSC1 −0.7295 4.80E−06 0.001 Protein of unknown function
 SSA4 −0.7232 6.34E−06 0.001 Heat shock protein that is highly induced upon stress
 INP53 −0.7212 6.92E−06 0.001 Polyphosphatidylinositol phosphatase
 RHO5 −0.7172 8.22E−06 0.001 Nonessential small GTPase of the Rho/Rac subfamily of Ras-like proteins
 ATP3 −0.7136 9.55E−06 0.001 Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase
 CUP1-1 −0.7127 9.91E−06 0.001 Metallothionein
 ADA2 −0.7094 1.14E−05 0.002 Transcription coactivator
 YPC1 −0.6983 1.78E−05 0.002 Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity
 NCE102 −0.694 2.10E−05 0.002 Protein of unknown function
 DDR2 −0.6931 2.18E−05 0.002 Multistress response protein
 YJL114W −0.6905 2.41E−05 0.002 Retrotransposon TYA Gag gene cotranscribed with TYB Pol
 UFD1 −0.6891 2.54E−05 0.003 Protein that interacts with Cdc48p and Npl4p
 ATP6 −0.6831 3.19E−05 0.003 Mitochondrially encoded subunit a of the F0 sector of mitochondrial F1F0 ATP synthase
 APM1 −0.6814 3.40E−05 0.003 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)
 HXT8 −0.672 4.77E−05 0.004 Protein of unknown function with similarity to hexose transporter family members
 PMP3 −0.668 5.49E−05 0.004 Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature
 FCP1 −0.6535 9.01E−05 0.007 Carboxy-terminal domain (CTD) phosphatase
 YNR047W −0.6529 9.21E−05 0.007 Putative protein kinase that
 ATC1 −0.6509 9.84E−05 0.007 Nuclear protein
 NDD1 −0.6504 9.98E−05 0.007 Transcriptional activator essential for nuclear division
 SIP18 −0.6498 1.02E−04 0.007 Protein of unknown function whose expression is induced by osmotic stress
 HXT13 −0.646 1.15E−04 0.008 Hexose transporter
 CYC1 −0.6455 1.17E−04 0.008 Cytochrome c
 YGR026W −0.6449 1.20E−04 0.008 Putative protein of unknown function
 SME1 −0.6386 1.46E−04 0.009 Core Sm protein Sm E
 YLR132C −0.6353 1.62E−04 0.01 Essential protein of unknown function
 TOM7 −0.634 1.69E−04 0.01 Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins
 YNL190W −0.63 1.91E−04 0.011 Cell wall protein of unknown function
 TRP4 −0.6282 2.02E−04 0.011 Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway
 SFT1 −0.6226 2.39E−04 0.012 Intra-Golgi v-SNARE
 COB −0.6199 2.58E−04 0.013 Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp
 PGD1 −0.6155 2.94E−04 0.015 Subunit of the RNA polymerase II mediator complex
 DCS2 −0.6142 3.06E−04 0.015 Nonessential
 GIS3 −0.6121 3.24E−04 0.016 Protein of unknown function
 YBR013C −0.6086 3.59E−04 0.016 Putative protein of unknown function
 NSR1 −0.6086 3.59E−04 0.016 Nucleolar protein that binds nuclear localization sequences
 YOR277C −0.6029 4.22E−04 0.019 Dubious open reading frame unlikely to encode a protein
 FCY1 −0.6026 4.25E−04 0.019 Cytosine deaminase
 JJJ2 −0.6012 4.42E−04 0.019 Protein of unknown function
Spearman correlations relative to Fd
 CUP1-2 0.8062 7.56E−08 0.0003 Metallothionein
 CUP1-1 0.7866 2.56E−07 0.0004 Metallothionein
 YLL032C 0.7857 2.69E−07 0.0004 Protein of unknown function that may interact with ribosomes
 APM1 0.777 4.43E−07 0.0005 Mu1-like medium subunit of the clathrin-associated protein complex (AP-1)
 SPC1 0.7372 3.38E−06 0.0028 Subunit of the signal peptidase complex (SPC)
 TVP23 0.7336 3.98E−06 0.0028 Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p
 GCN3 0.7309 4.49E−06 0.0028 Alpha subunit of the translation initiation factor eIF2B
 ATG1 0.7051 1.36E−05 0.006 Protein ser/thr kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway
 HSP12 0.696 1.95E−05 0.006 Plasma membrane localized protein that protects membranes from desiccation
 HSP30 0.695 2.02E−05 0.006 Hydrophobic plasma membrane localized
 SPG1 0.6903 2.43E−05 0.0065 Protein required for survival at high temperature during stationary phase
 ADA2 0.6884 2.61E−05 0.0065 Transcription coactivator
 GND2 0.6797 3.61E−05 0.0076 6-phosphogluconate dehydrogenase (decarboxylating)
 SSA4 0.6626 6.63E−05 0.0127 Heat shock protein that is highly induced upon stress
 CYC1 0.6566 8.14E−05 0.0133 Cytochrome c
 SPT7 0.6535 9.03E−05 0.0137 Subunit of the SAGA transcriptional regulatory complex
 YHR219W 0.651 9.79E−05 0.0137 Putative protein of unknown function with similarity to helicases
 YNL108C 0.6492 1.04E−04 0.0138 Putative protein of unknown function with similarity to Tfc7p and prokaryotic phosphotransfer enzymes
 YPL108W 0.6466 1.13E−04 0.0147 Cytoplasmic protein of unknown function
 YOR277C 0.6453 1.18E−04 0.0147 Dubious open reading frame unlikely to encode a protein
 YGR026W 0.6434 1.25E−04 0.0147 Putative protein of unknown function
 SIP18 0.6434 1.25E−04 0.0147 Protein of unknown function whose expression is induced by osmotic stress
 Q0182 0.6417 1.33E−04 0.0148 Dubious open reading frame unlikely to encode a protein
 OXR1 0.6358 1.59E−04 0.0171 Protein of unknown function required for normal levels of resistance to oxidative damage
 SMD2 0.6343 1.67E−04 0.0175 Core Sm protein Sm D2
 FCP1 0.6301 1.90E−04 0.0192 Carboxy-terminal domain (CTD) phosphatase
 SMA1 0.6294 1.94E−04 0.0192 Protein of unknown function involved in the assembly of the prospore membrane during sporulation
 YBL113C 0.6287 1.98E−04 0.0192 Helicase-like protein encoded within the telomeric Y element
 YJL114W 0.6274 2.07E−04 0.0193 Retrotransposon TYA Gag gene cotranscribed with TYB Pol
 INP53 0.621 2.51E−04 0.0221 Polyphosphatidylinositol phosphatase
 CRS5 0.6198 2.59E−04 0.0221 Copper-binding metallothionein
 SKS1 0.6196 2.61E−04 0.0221 Putative serine/threonine protein kinase
 POP6 0.6161 2.90E−04 0.0221 Subunit of both RNase MRP
 GIS3 0.6147 3.01E−04 0.0221 Protein of unknown function
 FMP48 0.6143 3.05E−04 0.0221 Putative protein of unknown function
 YHR097C 0.6143 3.05E−04 0.0221 Putative protein of unknown function
 RHO5 0.6143 3.05E−04 0.0221 Nonessential small GTPase of the Rho/Rac subfamily of Ras-like proteins
 TMA23 0.614 3.07E−04 0.0221 Nucleolar protein of unknown function implicated in ribosome biogenesis
 YGL117W 0.6103 3.42E−04 0.0227 Putative protein of unknown function
 SFT1 0.6103 3.42E−04 0.0227 Intra-Golgi v-SNARE
 SPS100 0.6089 3.56E−04 0.0227 Protein required for spore wall maturation
 MSC1 0.6079 3.66E−04 0.0227 Protein of unknown function
 ALG11 0.602 4.32E−04 0.024 Alpha-1
 SME1 0.602 4.32E−04 0.024 Core Sm protein Sm E
 YDL144C 0.6018 4.35E−04 0.024 Putative protein of unknown function
 DCS2 0.6016 4.37E−04 0.024 Nonessential
 YOL014W 0.6009 4.46E−04 0.0241 Putative protein of unknown function
 YJL156W-A 0.6005 4.51E−04 0.0241 Dubious open reading frame unlikely to encode a protein
 THI3 −0.714 9.39E−06 0.0052 Probable alpha-ketoisocaproate decarboxylase
 SCW4 −0.7056 1.33E−05 0.006 Cell wall protein with similarity to glucanases
 TIM21 −0.6984 1.77E−05 0.006 Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex)
 TPK1 −0.6953 2.00E−05 0.006 cAMP-dependent protein kinase catalytic subunit
 SNG1 −0.6947 2.05E−05 0.006 Protein involved in nitrosoguanidine (MNNG) resistance
 THI4 −0.6877 2.68E−05 0.0065 Thiazole synthase
 YLR444C −0.6862 2.84E−05 0.0066 Dubious open reading frame unlikely to encode a functional protein
 PUT1 −0.6815 3.38E−05 0.0074 Proline oxidase
 ACT1 −0.6739 4.45E−05 0.0089 Actin
 MEP2 −0.661 7.00E−05 0.0128 Ammonium permease involved in regulation of pseudohyphal growth
 HPA3 −0.6588 7.55E−05 0.0133 D-Amino acid N-acetyltransferase
 RPS21A −0.6577 7.84E−05 0.0133 Protein component of the small (40S) ribosomal subunit
 DAN2 −0.6543 8.77E−05 0.0137 Cell wall mannoprotein with similarity to Tir1p
 BUD31 −0.6515 9.65E−05 0.0137 Protein involved in bud-site selection
 YLR179C −0.6506 9.94E−05 0.0137 Protein of unknown function
 PET18 −0.643 1.27E−04 0.0147 Protein required for respiratory growth and stability of the mitochondrial genome
 ARC1 −0.6412 1.35E−04 0.0148 Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p)
 PAU1 −0.6283 2.01E−04 0.0192 Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions
 HRT3 −0.6221 2.43E−04 0.0221 Putative SCF-ubiquitin ligase F-box protein
 CDC7 −0.6192 2.64E−04 0.0221 DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p
 RNR2 −0.6187 2.68E−04 0.0221 Ribonucleotide-diphosphate reductase (RNR)
 YIL067C −0.6183 2.71E−04 0.0221 Uncharacterized protein of unknown function
 PRE1 −0.614 3.07E−04 0.0221 Beta 4 subunit of the 20S proteasome
 URA7 −0.6118 3.27E−04 0.0227 Major CTP synthase isozyme (see also URA8)
 DBP5 −0.6105 3.40E−04 0.0227 Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus
 PAU7 −0.6092 3.53E−04 0.0227 Part of 23-member seripauperin multigene family
 ERG20 −0.6089 3.56E−04 0.0227 Farnesyl pyrophosphate synthetase
 YAR069C −0.6087 3.58E−04 0.0227 Dubious open reading frame unlikely to encode a protein
 JSN1 −0.6083 3.63E−04 0.0227 Member of the Puf family of RNA-binding proteins
 RPL23B −0.6072 3.73E−04 0.0228 Protein component of the large (60S) ribosomal subunit
 CHO2 −0.6045 4.03E−04 0.024 Phosphatidylethanolamine methyltransferase (PEMT)
 CDC45 −0.6034 4.16E−04 0.024 DNA replication initiation factor
 YNR048W −0.6031 4.19E−04 0.024 Protein proposed to interact with phospholipid translocases
 SOL2 −0.6016 4.37E−04 0.024 Protein with a possible role in tRNA export
 GLN1 −0.6 4.57E−04 0.0241 Glutamine synthetase (GS)
Spearman correlations relative to Nass
 PAU7 0.6761 6.32E−05 0.019 Part of 23-member seripauperin multigene family
 SNG1 0.6568 8.07E−05 0.019 Protein involved in nitrosoguanidine (MNNG) resistance
 PUT1 0.6556 1.22E−04 0.023 Proline oxidase
 DAN2 0.6547 1.25E−04 0.023 Cell wall mannoprotein with similarity to Tir1p
 PAU8 0.6383 2.06E−04 0.027 Hypothetical protein
 MEP2 0.6383 2.06E−04 0.027 Ammonium permease involved in regulation of pseudohyphal growth
 PLB2 0.6245 3.05E−04 0.033 Phospholipase B (lysophospholipase) involved in phospholipid metabolism
 LHP1 0.6214 3.32E−04 0.034 RNA binding protein required for maturation of tRNA and U6 snRNA precursors
 PAU13 0.6182 3.62E−04 0.034 Putative protein of unknown function
 PAU1 0.6182 3.62E−04 0.034 Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions
 MOG1 0.6151 3.93E−04 0.034 Conserved nuclear protein that interacts with GTP-Gsp1p
 PAU14 0.6142 4.03E−04 0.034 Hypothetical protein
 PAU4 0.6133 4.13E−04 0.034 Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions
 SRB7 0.6125 4.23E−04 0.034 Subunit of the RNA polymerase II mediator complex
 PAU10 0.6071 4.87E−04 0.038 Hypothetical protein
 CBR1 0.6027 5.47E−04 0.038 Microsomal cytochrome b reductase
 YBR016W 0.6018 5.60E−04 0.038 Plasma membrane protein of unknown function
 PEX29 0.6009 5.73E−04 0.039 Peroxisomal integral membrane peroxin
 YKL050C −0.8091 1.11E−06 0.005 Protein of unknown function
 MRS1 −0.7499 4.30E−06 0.009 Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1)
 YBL113C −0.7344 7.64E−06 0.01 Helicase-like protein encoded within the telomeric Y element
 YHR097C −0.7286 9.51E−06 0.01 Putative protein of unknown function
 YJL225C −0.7152 1.57E−05 0.014 Putative protein of unknown function
 YMR086W −0.709 1.98E−05 0.015 Protein of unknown function that may interact with ribosomes
 YGR251W −0.6974 3.02E−05 0.018 Essential protein required for maturation of 18S rRNA
 COX16 −0.6948 3.32E−05 0.018 Mitochondrial inner membrane protein
 TOA1 −0.6881 4.20E−05 0.019 TFIIA large subunit
 YPL080C −0.6823 5.12E−05 0.019 Dubious open reading frame unlikely to encode a protein
 PEX14 −0.6796 5.61E−05 0.019 Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery
 DDC1 −0.6739 6.80E−05 0.019 DNA damage checkpoint protein
 YRF1-3 −0.6734 6.90E−05 0.019 Helicase encoded by the Y element of subtelomeric regions
 YLL066C −0.6707 7.54E−05 0.019 Putative protein of unknown function with similarity to helicases
 YLR326W −0.669 7.99E−05 0.019 Putative protein of unknown function
 TMA23 −0.6672 8.46E−05 0.019 Nucleolar protein of unknown function implicated in ribosome biogenesis
 PHM7 −0.6659 8.83E−05 0.019 Protein of unknown function
 IES5 −0.6637 6.38E−05 0.019 Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions
 NSA1 −0.6636 9.48E−05 0.019 Constituent of 66S pre-ribosomal particles
 MTF1 −0.6515 9.65E−05 0.019 Mitochondrial RNA polymerase
 YMR244C-A −0.6507 1.42E−04 0.023 Putative protein of unknown function
 MDM12 −0.6503 1.44E−04 0.023 Mitochondrial outer membrane protein
 YMR306C-A −0.6489 1.50E−04 0.023 Dubious open reading frame unlikely to encode a functional protein
 ERG24 −0.6489 1.50E−04 0.023 C-14 sterol reductase
 ENP2 −0.6485 1.52E−04 0.023 Essential nucleolar protein of unknown function
 AIM23 −0.6458 1.64E−04 0.024 Putative protein of unknown function
 YHR219W −0.6392 2.00E−04 0.027 Putative protein of unknown function with similarity to helicases
 YDL173W −0.6374 2.11E−04 0.027 Putative protein of unknown function
 VOA1 −0.6352 2.25E−04 0.027 Putative protein of unknown function
 CUE5 −0.6352 2.25E−04 0.027 Protein containing a CUE domain that binds ubiquitin
 YOR021C −0.6316 2.49E−04 0.029 Putative protein of unknown function
 YAR028W −0.6298 2.62E−04 0.03 Putative integral membrane protein
 GFD1 −0.6267 2.86E−04 0.031 Coiled-coiled protein of unknown function
 JID1 −0.6263 2.14E−04 0.027 Probable Hsp40p cochaperone
 SCM3 −0.6209 3.36E−04 0.034 Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones
 YLR363W-A −0.6205 3.40E−04 0.034 Putative protein of unknown function
 YOR289W −0.616 3.84E−04 0.034 Putative protein of unknown function
 IRC25 −0.6147 3.98E−04 0.034 Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome
 TPK3 −0.6142 4.03E−04 0.034 cAMP-dependent protein kinase catalytic subunit
 HCA4 −0.6133 4.13E−04 0.034 Putative nucleolar DEAD box RNA helicase
 SGF11 −0.6102 4.49E−04 0.036 Integral subunit of SAGA histone acetyltransferase complex
 YRF1-8 −0.608 4.76E−04 0.037 One of several telomeric Y element-encoded DNA helicases
 CUS1 −0.6044 5.22E−04 0.038 Protein required for assembly of U2 snRNP into the spliceosome
 GLC8 −0.6031 5.41E−04 0.038 Regulatory subunit of protein phosphatase 1 (Glc7p)
 YML133C −0.6027 5.47E−04 0.038 Putative protein of unknown function with similarity to helicases
 SPO13 −0.6018 5.60E−04 0.038 Meiosis-specific protein
 ELA1 −0.6004 5.79E−04 0.039 Elongin A

For each gene, the P value, the adjusted P value (Benjamini and Hochberg adjustment), and function are indicated.