Table 5 . Functional categories enriched in heterozygous diploid mutants with a fitness advantage during fermentation.
| Functional Categorya | Genesb | Total Genes Observed | Total Genes in Dataset | Pc |
|---|---|---|---|---|
| Ribosomal proteins | DBP9, MRPL1, MRPL10, MRPL16, MRPS16, MRPS35, MRPS5, PET123, RPL10, RPL12A, RPL13B, RPL17B, RPL21A, RPL22A, RPL23B, RPL24A, RPL25, RPL26B, RPL2B, RPL34A, RPL36A, RPL40B, RPL41B, RPL6B, RPP1B, RPS0A, RPS12, RPS14B, RPS16A, RPS19A, RPS19B, RPS1B, RPS2, RPS22B, RPS23B, RPS24A, RPS24B, RPS26B, RPS29B, RPS31, RPS4A, RPS8A, RRP15, RSA3, RSM10, RSM23 | 46 | 198 | 1.5 × 10−8 |
| MIPS 12.01.01 |
MIPS, Munich Information Center for Protein Sequences.
a
Enrichment of functional categories was first defined according to Funspec (Robinson et al. 2002) with P ≤ 0.01. Additional genes were added manually.
b
Genes listed are deletion mutants with a 2-fold or greater increase in abundance compared with control in at least three of the fermentation time points.
c
P value calculation in Materials and Methods.
d
Manually annotated.