Figure 7 .
AD hybrid isolates exhibit phenotypic plasticity. Most AD hybrid isolates are resistant to the antifungal drug FK506 (left) and the progeny of the self-fertile strain CDC228 (aADα), which is resistant the antifungal drug FK506, have altered FK506 resistance (right). After growing for 48 hr on YPD + FK506 (1 µg/ml) medium at 37°, five AD hybrid isolates (ZG290, NC34-21, MMRL1365, MMRL774, and MMRL752) exhibited resistance compared with the H99 and JEC21 haploid strains (left). After growing for 48 hr on YPD + FK506 (1 µg/ml) medium at 37°C, progeny P5 was sensitive to FK506 (right).