. Author manuscript; available in PMC: 2013 Jan 13.

Published in final edited form as: Chem Res Toxicol. 2011 Dec 14;25(1):130–139. doi: 10.1021/tx200333g

Table 3.

Concentrations (µM) of AA-I and the metabolites at the 70–80 min period in perfusates and urines collected from isolated kidneys A and B perfused with 50 µM AA-I and the urine of rats (24 hr collection) subcutaneously injected with AA-I (2 mg) (Standard Deviation in parentheses).

	IPK experiments				Subcutaneously injected rats
	Kidney A		Kidney B		Subcutaneously injected rats
Compound	Perfusate	Urine	Perfusate	Urine	Urine
AA-I (1)	16.07	0.48	23.8	0.94	0.20 (0.05)
AA-Ia (2)	1.24	0.68	0.42	4.38	24.1 (4.0)
L-I (3)	0.002	0.053	0.018	0.055	0.018 (0.013)
L-Ia (4)	0.010	0.16	0.024	non-determined	5.76 (2.43)
AA-Ia-O-S (5)	nd	0.36	nd	0.74	nd/traces
L-Ia-O-G (6)	nd	0.031	0.014	0.021	0.15 (0.12)
L-Ia-O-S (7)	nd	nd	nd	nd	0.15 (0.07)

nd: non-detected