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Bilateral SNr lesions did not alter PTZ-enhanced convulsions. Bilateral caudolateral SNr-lesioned, sham-lesioned, and no surgery control groups all received a single dose of PTZ (30 mg/kg, i.p.). HICs were measured 1, 3, 5, 8, 10, 15, 20, 35, 50, and 65 min postPTZ administration. PTZ-enhanced convulsions, calculated as the AUC, did not differ between caudolateral SNr-lesioned (n = 4), sham-lesioned (n = 6), and unoperated control (n = 6) D2 mice (H(2,16) = 0.43; p = 0.8).
