Table 2.
Congenic |
D2 |
ANOVA | post hoc | |||
---|---|---|---|---|---|---|
Saline | Ethanol | Saline | Ethanol | |||
Rostral SNr | 0 ± 0 | 290 ± 83 | 1 ± 0 | 771 ± 62 | H(3,40) = 27.4; p < 10−4 | p = 9.6 × 10−3 |
Caudal SNr | 2 ± 1 | 374 ± 87 | 4 ± 2 | 766 ± 38 | H(3,40) = 25.5; p < 10−4 | p = 1.2 × 10−2 |
Dorsomedial SNr | 0 ± 0 | 616 ± 190 | 4 ± 3 | 1515 ± 118 | H(3,40) = 25.0; p < 10−4 | p = 1.5 × 10−2 |
Ventral pallidum | 1 ± 1 | 285 ± 74 | 0 ± 0 | 818 ± 45 | H(3,40) = 29.7; p < 10−4 | p = 2.6 × 10−4 |
Rostromedial LGP | 0 ± 0 | 385 ± 98 | 0 ± 0 | 996 ± 54 | H(3,40) = 29.6; p < 10−4 | p = 6.0 × 10−3 |
Subthalamic nucleus | 0 ± 0 | 1256 ± 313 | 12 ± 10 | 2611 ± 130 | H(3,40) = 25.2; p < 10−4 | p = 1.9 × 10−3 |
The number of labeled cells/mm2 ± SEM in six brain regions is shown. Densities of c-Fos-positive neurons in discrete brain regions. The densities of c-Fos-positive neurons were measured throughout the rostrocaudal extent of the six brain regions that displayed significant effects of strain in Table 1. Values represent the mean density of c-Fos-immunoreactive neurons ±SEM/mm2. In each region, the results of a Kruskal–Wallis one-way ANOVA and the post hoc comparison between ethanol withdrawn congenic and background strain mice are indicated.