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. Author manuscript; available in PMC: 2012 Feb 9.
Published in final edited form as: J Lipid Res. 2006 Sep 1;47(12):2738–2753. doi: 10.1194/jlr.M600302-JLR200

TABLE 1.

Bias error in FSR using TTR slope/plateau instead of enrichment values

g, Top of Line Plateau Enrichment
5 8 10 15
% %
0.1 −4.93 −7.93 −9.93 −14.94
0.5 −4.64 −7.65 −9.66 −14.68
1.0 −4.28 −7.30 −9.32 −14.36

FSR, fractional synthetic rate; TTR, tracer-to-tracee ratio. The column heads give four typical plateau enrichment values. The left column gives three possible values for the top enrichment on the linear portion of the apolipoprotein enrichment data. The other columns give the bias error in percent in computing FSR from TTR data for each combination of plateau enrichment and g. Thus, if the enrichment plateau is 10% and the linear portion increases from 0 to 0.5%, FSR calculated from the TTR plateau and the slope of the TTR data will be 9.66% lower than the correct FSR (from the enrichment plateau and the slope of the enrichment data).