Table 1.
Patients’ characteristics
| Feature | NSCLC histologic typea |
|||
| Adenocarcinoma (n = 299), n (%) | Squamous carcinoma (n = 164), n (%) | P value | Total (N = 463), n (%) | |
| Median age (range), years | 65 (32–89) | 68 (44–90) | 0.0353 | 66 (32–89) |
| Sex | 0.0032 | |||
| Male | 134 (44.8) | 97 (59.1) | 232 (50.1) | |
| Female | 165 (55.2) | 67 (40.9) | 231 (49.9) | |
| Smoking statusb | <0.0001 | |||
| Never | 48 (16.1) | 1 (0.6) | 49 (10.6) | |
| Former | 133 (44.5) | 79 (48.2) | 212 (45.8) | |
| Current | 118 (39.5) | 84 (51.2) | 202 (43.6) | |
| Race | 0.87 | |||
| Caucasian | 273 (91.3) | 149 (90.9) | 422 (91.1) | |
| Others | 26 (8.7) | 15 (9.1) | 41 (8.9) | |
| (Neo)adjuvant treatment | 0.0159 | |||
| No | 140 (46.8) | 73 (44.5) | 213 (46.0) | |
| Adjuvant | 19 (6.4) | 21 (12.8) | 40 (8.6) | |
| Neoadjuvant | 84 (28.1) | 45 (27.4) | 129 (27.9) | |
| Both | 26 (8.7) | 5 (3.0) | 31 (6.7) | |
| Unknown | 30 (10.0) | 20 (12.2) | 50 (10.8) | |
| T categoryc | 0.35 | |||
| 1 | 120 (40.1) | 58 (35.4) | 178 (38.4) | |
| 2 | 145 (48.5) | 85 (51.8) | 230 (49.7) | |
| 3 | 11 (3.7) | 11 (6.7) | 22 (4.8) | |
| 4 | 23 (7.7) | 10 (6.1) | 33 (7.1) | |
| N categoryc | 0.0460 | |||
| 0 | 214 (71.8) | 107 (65.6) | 321 (69.6) | |
| 1 | 42 (13.8) | 37 (22.7) | 78 (16.9) | |
| 2 | 43 (14.4) | 19 (11.7) | 62 (13.4) | |
| x | 1 (0.3) | 1 (0.6) | 2 (0.4) | |
| Final stagec | 0.25 | |||
| I | 184 (61.5) | 93 (56.7) | 277 (59.8) | |
| II | 82 (27.4) | 58 (35.4) | 140 (30.2) | |
| III | 21 (7.0) | 10 (6.1) | 31 (6.7) | |
| IV | 12 (4.0) | 3 (1.8) | 15 (3.2) | |
Never smoker: an adult who has never smoked or who has smoked <100 cigarettes in his or her lifetime; former smoker: an adult who has smoked at least 100 cigarettes in his or her lifetime but who had quit smoking at the time of interview; current smoker: an adult who has smoked 100 cigarettes in his or her lifetime and who currently smokes cigarettes.
Values are number of cases unless otherwise indicated.
Smoking history was assigned based on the CDC definitions (http://www.cdc.gov/nchs/nhis/tobacco/tobacco_glossary.htm, accessed on 29 June 2010).
According to the American Joint Committee on Cancer Staging Manual sixth edition.
CDC, Center for Disease Control and Prevention; N, node; NSCLC, non-small-cell lung cancer; T, tumor.