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T cell phenotypic subsets producing IFN-γ within an alloCTL preparation before and after restimulation with relevant target glioma cells.
| alloCTL ± relevant target glioma | T-cell subset phenotype | % of the total CD3+ cells | % of CD3+ subset also IFN-γ+ | IFN-γ MFI |
|---|---|---|---|---|
| alloCTL | CD3+/CD8+/CD69+ | 10.5% | 52.1% | 500 |
| alloCTL + target glioma | CD3+/CD8+/CD69+ | 62.7% | 34.7% | 2543 |
| alloCTL | CD3+/CD4+/CD69+ | 35.3% | 0.70% | 254 |
| alloCTL + target glioma | CD3+/CD4+/CD69+ | 80.0% | 0.90% | 1605 |
