Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic diagram of the proposed sequence of events whereby PKCβ deficiency leads to a reduction in metabolic efficiency. Elevated adipose PKCβ expression in ob/ob mice suppresses β-adrenergic signaling and thereby reduces UCP-1 expression in iWAT and prevents WAT catabolic activity.
