Figure 6. Adoptive transfer of CD8⁺ T cells from p210 immunized donors recapitulated the effect of p210 immunization.

(A) CD8⁺ T cell recipient mice from p210/cBSA/alum immunized donors developed significantly smaller atherosclerotic lesions compared to the recipient mice of CD8⁺ T cells from other 2 groups (N = 9–10 each group; P<0.05). This effect was negated when CD25⁺ cells were depleted from the donor pool (B; 8–10 each group). Data were analyzed by ANOVA followed by Newman-Keuls multiple group comparison.