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. 2012 Feb 9;7(2):e31411. doi: 10.1371/journal.pone.0031411

Table 3. Risk factors associated with mean BPD z-score as a measure of early fetal growth restriction.

Univariate Multivariate (n = 2972)
Frequency (%) Coefficient (95% CI) P-value Coefficient (95%CI) P-value
Teenager No 3,210 (84.9)
Yes 569 (15.1) −0.02 (−0.13, 0.08) 0.66 * NS
Primigravida No 2,848 (75.4)
Yes 931 (24.6) 0.07 (−0.02, 0.16) 0.10 * NS
Smoking No 2,893 (76.8)
Yes 876 (23.2) 0.04 (−0.05, 0.12) 0.43 * NS
Low MUAC No 2,801 (96.0)
Yes 116 (4.0) 0.07 (−0.14, 0.29) 0.51 * NS
Short No 2,995 (89.2)
Yes 362 (10.8) 0.04 (−0.09, 0.16) 0.58 * NS
Low BMI No 2,738 (81.6)
Yes 619 (18.4) 0.18 (0.08, 0.28) 0.001 0.15 (0.04, 0.26) 0.005
Weight loss No 2,396 (80.5)
Yes 581 (19.5) 0.09 (−0.02, 0.19) 0.10 0.11 (0.00, 0.21) 0.05
Anaemia No 2152 (56.9)
Yes 1627 (43.1) 0.16 (0.09, 0.24) <0.001 $
Malaria No 3,443 (91.1)
Yes 336 (8.9) 0.47 (0.34, 0.60) <0.001 0.50 (0.36, 0.63) <0.001
Symptomatic malaria No 169 (50.6)
Yes 165 (49.4) 0.05 (−0.19, 0.30) 0.68 * NS
Newborn gender M 1,936 (51.2)
F 1,843 (48.8) 0.25 (0.18, 0.33) <0.001 0.25 (0.17,0.34) <0.001

Significant differences are shown in bold.

BMI body mass index, MUAC middle upper arm circumference, NS not significant.

*Not included in the multivariate analysis.

$

Anaemia was highly collinear with malaria, and the co-variates in the multivariate model were unchanged when anaemia was adjusted for or not.