Table 4. Initial concentrations of anchored molecule species in the simulation.
Anchored Molecules | Spine Cytosol (nM)# | Focal Dendrite Submembrane (picoSD)* |
R | 153.9 | 20.3 |
G | 8158.3 | 1012.5 |
GR | 1255.5 | 160.8 |
GαGTP | 8.1 | 0.0 |
GαGDP | 90.0 | 12.0 |
Gβγ | 43.2 | 0.0 |
AC | 7428.0 | 887.6 |
ACGαGTPCa-ATP | 14.0 | 0.0 |
ACGαGTP-ATP | 114.5 | 19.0 |
ACCa | 2376.0 | 259.9 |
PKA | 7050.0 | 1130.0 |
PKAcAMP2 | 925.0 | 155.0 |
PKAcAMP4 | 137.5 | 30.0 |
PKAc | 300.0 | 60.0 |
PKAr | 150.0 | 30.0 |
Only one of these concentrations applied, depending on whether molecules were anchored in the spine, or in the dendrite.
*Molecules initialized in the dendrite submembrane are specified in picoMoles per µm2 (picoSD).
Molecules initialized in the spine cytosol were excluded from the PSD, except for PKA species.