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. Author manuscript; available in PMC: 2012 Feb 9.
Published in final edited form as: Eur J Med Chem. 2010 Jul 24;45(10):4682–4686. doi: 10.1016/j.ejmech.2010.07.030

Table 2.

Evaluation of drug likeness properties.

Compounds MW <500 C log P <5 Number of O and N <10 Number of OH and NH <5 N rotatable bonds <10 N-violations ≯1
1a 306.32 1.44 5 0 3 0
1g 340.76 1.97 5 0 3 0
1h 375.20 2.45 5 0 3 0
1l 351.31 1.35 8 0 4 0