Table 1. Estimates of the human single nucleotide mutation rate (μ) obtained by large-scale sequencing of relatives.

Reference	Sequencing method	No. mutations detected	Mutation rate, μ (× 10−8)
Xue et al. (2009)	Illumina	4	3.0 (Chr Y)
Roach et al. (2010)	Array based	28	1.1
Awadalla et al. (2010)	Sanger	4	1.4
1000 Genomes Project Consortium (2010)	Illumina	49 (European)	1.2
1000 Genomes Project Consortium (2010)	Illumina	35 (Yoruba)	1.0
Weighted average			1.1 (excluding Xue et al. 2009)