Table 2 . Mutations recovered from the screen.
| Function | Fly gene name | Vertebrate homologs | CG no. | Cytology | No. of alleles |
|---|---|---|---|---|---|
| EGFR/MAPK pathway | corkscrew (csw) | SHP-2 | 3954 | 2D1–2 | 7 |
| pole hole (phl) | Raf | 2845 | 3A1 | 6 | |
| Downstream of raf1 (Dsor1) | MEK/MAPKK | 15793 | 8D2–3 | 5 | |
| Wingless pathway | shaggy (sgg) | GSK3β | 2621 | 3A8–3B1 | 9 |
| Casein Kinase 1α (CK1α) | CK1α | 2028 | 11B7 | 1 | |
| Notch pathway | Notch (N) | N | 3936 | 3C7–9 | 1 |
| Endocytosis/cytoskeleton | shibire (shi) | Dynamin | 18102 | 13F18 | 1 |
| Actin-related protein 14D (Arp14D) | Arp2 | 9901 | 14E1 | 1 | |
| Transcriptional regulation | nejire (nej) | CBP | 15319 | 8F7–9 | 2 |
| lozenge (lz) | AML1 | 1689 | 8D5–6 | 3 | |
| Adhesion/polarity | furrowed (fw) | P-selectin | 1500 | 11A1 | 3 |
| discs large 1 (dlg1) | DLG1 | 1725 | 10B6–10 | 3 | |
| Cell cycle regulation | retina aberrant in pattern (rap) | Cdh1/Fzr | 3000 | 4C11–12 | 6 |
| Unidentified genes | Complementation group A | 2D1–2;3C5–6 | 4 | ||
| Complementation group B | 2D1–2;3A1–2 | 2 | |||
| Complementation group C | 5A1–6C | 2 | |||
| Other hits | 63 |