Table 2.

Rare-Variant Analysis in Individuals with MFDM^a

Any X of Four Individuals	1	2	3	4
Genes containing missense, nonsense, in/del, or splice-site variants	2,523	196	18	2
Allele frequency of ≤1% in dbSNP131, 1000 Genomes, and 120 local exomes	1,474	161	8b	1 (MUC4)c

^aWith a dominant model of disease.

^bIncluding EFTUD2.

^cPrivate MUC4 variants are a frequent finding at our center; therefore, this gene was deliberately excluded from further analysis.