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. Author manuscript; available in PMC: 2012 Feb 10.

Published in final edited form as: Phys Med Biol. 2008 Jul 8;53(15):4107–4121. doi: 10.1088/0031-9155/53/15/007

Comparison of 100% isodose lines of the reference clinical plan (RCP) (dotted line) and the homogeneous Cimmino optimized plan (solid line). Homogeneous optical properties (µ_a = 0.3 cm−1 and µ_s' = 14 cm−1) are assumed to generate the optimal plans. The isodose lines were calculated with the FEM model using heterogeneous optical properties (as illustrated in Fig. 2) Source locations are marked by “”.

Inline graphic — Comparison of 100% isodose lines of the reference clinical plan (RCP) (dotted line) and the homogeneous Cimmino optimized plan (solid line). Homogeneous optical properties (µ_a = 0.3 cm−1 and µ_s' = 14 cm−1) are assumed to generate the optimal plans. The isodose lines were calculated with the FEM model using heterogeneous optical properties (as illustrated in Fig. 2) Source locations are marked by “”.