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. 2012 Jan;51(1):83–87.

Table 2.

Time to event (min; mean ± SE) under various euthanasia regimens

Pairwise comparison P valuea
Event Time to event Euthanizing agent Xylazine + acepromazine Xylazine only Xylazine + KCl MS222 Pentobarbital
Cardiac arrest
0.14 ± 0.10 Xylazine + acepromazine <0.0001 0.2139 0.0005 <0.0001
0.34 ± 0.10 Xylazine only 0.0032 0.0005 <0.0001
0.20 ± 0.12 Xylazine + KCl 0.0004 <0.0001
0.65 ± 0.47 MS222 0.0003
1.04 ± 0.58 Pentobarbital
Purposeful movement
4.63 ± 0.61 Xylazine + acepromazine 0.0422 0.1364 <0.0001 <0.0001
>5.00 Xylazine only 0.0037 <0.0001 <0.0001
4.08 ± 1.05 Xylazine + KCl <0.0001 <0.0001
1.16 ± 1.12 MS222 0.7519
1.03 ± 0.58 Pentobarbital
a

χ2 test subsequent to generalized estimating equations analyses