Table 5.
Independent predictors of surgical site infection (SSI) in 2332 hepatectomy patients
Variable | Multivariate odds ratio (95% confidence interval, P-value) | |
---|---|---|
Superficial, deep or organ space SSI (n = 268, 11.5%) | Organ space SSI only (n = 140, 6.0%) | |
Preoperative open wound/infection | All patients with this variable had SSIa | 1.81 (1.03–3.20, P = 0.039) |
Serum sodium > 145 mmol/l | 6.05 (2.30–15.93, P < 0.001) | 6.25 (2.36–16.55, P < 0.001) |
Serum albumin, per mg/dl from mean | 0.67 (0.49–0.91, P = 0.011) | 0.70 (0.52–0.95, P = 0.022) |
Total bilirubin > 1.0 | 1.70 (1.05–2.77, P = 0.032) | 1.87 (1.19–2.95, P = 0.007) |
On dialysis | Not in model | 4.46 (1.14–17.45, P = 0.032) |
Smoker within 1 year of procedure | Not in model | 1.66 (1.08–2.54, P = 0.021) |
Operative time, per min from mean | 1.003 (1.001–1.004, P < 0.001) | 1.003 (1.002–1.004, P < 0.001) |
Because all patients with this variable experienced SSI, the odds ratio was extremely large (>100). No precise odds ratio is estimable from this patient population; however, it is clearly a strong predictor.