Fig. 2.

In vitro migration and wound closure is increased by FGF-2 treatment in combination with syndecan-4 proteoliposomes. Confluent monolayers of endothelial cells were wounded by scraping with a plastic cell scraper. Wound closure and cell migration was examined at various times with phase-contrast microscopy. (A) Quantitative analysis of wound edge closure following wounding and in the presence of various treatments. (B) Wound-healing assay shows increased wound edge migration with syndecan-4 proteoliposome treatment. (Scale bar, 100 μm.) *Statistically significant difference between samples (P < 0.05).