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HFD prevents the block of autophagy flux, myopathy, and perinatal mortality in dKO mice. (A) H&E sections of TA muscle of 3-mo-old control and dKO mice, fed with either normal chow or HFD for 8 wk. (Scale bars, 40 μm.) (B) Western blot analysis for autophagy markers LC3 I-II and p62 in control and dKO mice, fed with normal chow or HFD for 8 wk. Tubulin was used as loading control.
