Table 5.
In Situ Detection of LAM and PGL-I in the Lesional Skin of MB and PB Patients Released from Treatment
Patients RFT | Localization | Positive staining pattern | |
---|---|---|---|
LAM* | PGL-I† | ||
MB (n = 14; BI 0–1+) | Granuloma | 1 /14 | 1 /14 |
Scattered cells | 0 /14 | 6 /14 | |
Other locations‡ | 2 /14 | 2 /14 | |
PB (n = 7; BI 0) | Granuloma | 0 /7 | 0 /7 |
Scattered cells | 0 /7 | 1 /7 | |
Other locations | 0 /7 | 0 /7 |
In situ presence of LAM and PGL-I was determined by immunohistochemical analysis using MAbs F 30-5 and DZ-1, respectively. MB, multibacillary; PB, paucibacillary; RFT, release from treatment.
*Granular staining pattern.
†Staining pattern was as clumps (see inset in Figure 3C▶ ).
‡Around the vessel or nerve fibers.