. Author manuscript; available in PMC: 2012 Nov 9.

Published in final edited form as: J Am Chem Soc. 2011 Oct 14;133(44):17869–17877. doi: 10.1021/ja207318n

Table 5.

MICs of Arylomycin C-C₁₆ (μg/ml) against mutants known to be sensitive to arylomycin A- and B-C₁₆

Strain	Arylomycin A-C₁₆	Arylomycin C-C₁₆
S. aureus NCTC 8325	>128	>128
S. aureus P29S PAS8001^b	2	4
E. coli MG1655	>128	>128
E. coli P84L PAS0260^b	2	2
P. aeruginosa PAO1	>128	>128
P. aeruginosa P84L PAS2008^b	8	16

included for comparison.¹⁹

Constructed from their Arylomycin A-C₁₆ respective wild type strains by mutation of the resistance-conferring proline to either serine (S. aureus) or leucine (E. coli and P. aeruginosa).¹⁸