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Bezafibrate attenuates astrogliosis in R6/2 brains. Photomicrographs showing GFAP immunoreactivity in the striatum of wild-type and R6/2 mice with or without bezafibrate treatment. GFAP-labeled hypertrophied astrocytes (inset) are evident in the striatum of R6/2 mice. Astrogliosis in the HD striatum is reduced by bezafibrate treatment.
