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. Author manuscript; available in PMC: 2012 Feb 10.
Published in final edited form as: Eur J Immunol. 2010 Nov;40(11):2969–2975. doi: 10.1002/eji.201040895

Figure 1. Schematic of possible pathway of MDSC differentiation in cancer.

Figure 1

Blue dashed lines denote myeloid cell differentiation under physiologic conditions. Black solid line shows proposed development of MDSC in tumor-bearing host. HSC – hematopoietic stem cells, CMOP – common myeloid progenitor, MΦ – macrophages, DC –dendritic cells, T – T cells. See detailed explanation in the text.