Table 1.
Minor allele frequency of SNPs from the JAK2 locus in PV
| No. | SNP | Minor alleles in PV (n = 28) | Minor alleles in control (n = 28) | P value* (Chi square test) | Odds ratio (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|---|
| No | Yes (homo/hetero) | % | No | Yes (homo/hetero) | % | ||||
| 1 | rs10974944 (c→g) | 7 | 21 (15/6) | 75 | 17 | 11 (3/8) | 39.2 | 0.0069 | 4.64 (1.49-14.55) |
| 12 | rs12686652 (c→g) | 6 | 22 (21/1) | 78.6 | 14 | 14 (5/9) | 50 | 0.0257 | 3.67 (1.14-11.79) |
| 13 | rs12335546(c→t) | 6 | 22 (21/1) | 78.6 | 19 | 9 (1/8) | 32.1 | 0.0005 | 7.74 (2.33-25.75) |
| 19 | rs4495487 (t→c) | 7 | 21 (21/0) | 75 | 23 | 5 (3/2) | 17.8 | < 0.0001 | 13.8 (3.79-50.21) |
| 22 | rs1028730 (g→a) | 6 | 22 (21/1) | 78.5 | 19 | 9 (2/7) | 32.1 | 0.0005 | 7.74 (2.33-25.75) |
| 24 | rs12343867(t→c) | 7 | 21 (21/0) | 75 | 17 | 11 (4/9) | 39.3 | 0.0069 | 4.64 (1.48-14.55) |
* P values were calculated by the cases having minor alleles (homozygous and heterozygous) and cases without minor alleles.