Table 3.

Mutation frequency of the FHV genome

Sample	Average	First position	Second position	Third position
FHV virion RNA 1	8.7 × 10-4	8.5 × 10-4	5.8 × 10-4	11.9 × 10-4
FHV virion RNA 1 + RNA 3	7.0 × 10-4	7.1 × 10-4	7.3 × 10-4	6.6 × 10-4
FHV virion RNA 2	9.8 × 10-4	6.1 × 10-4	5.8 × 10-4	18.9 × 10-4
FHV VLP RNA 2	7.4 × 10-4	8.4 × 10-4	7.9 × 10-4	8.4 × 10-4

Mutation frequency is expressed as the average number of mismatched nucleotides per 10,000 aligned nucleotides for both authentic FHV virions and FHV VLPs. The averages over the whole gene and at each codon position for the ORFs of both RNA 1 and RNA 2 are shown.