Table 2. GSEA analysis of published gene sets.
PATHWAY/GENE SET | SIZEa | ESb | NESc | p-val | FDR | CSd | REFe |
LS vs NL: | |||||||
PSORIASIS_SF_UP | 551 | 0.88 | 3.89 | 0.000 | 0.000 | 0.86 | [20] |
PSORIASIS_SF_DOWN | 680 | −0.83 | −4.29 | 0.000 | 0.000 | ||
Relapse vs Week 12: | |||||||
PSORIASIS_SF_UP | 569 | 0.85 | 4.26 | 0.000 | 0.000 | 0.84 | [20] |
PSORIASIS_SF_DOWN | 694 | −0.82 | −4.25 | 0.000 | 0.000 | ||
IL22 KC_UP | 11 | 0.86 | 2.16 | 0.000 | 0.000 | 0.84 | [21] |
IL22 KC_DOWN | 10 | −0.82 | −2.05 | 0.000 | 0.000 | ||
IFNG KC_UP | 907 | 0.42 | 2.19 | 0.000 | 0.000 | 0.34 | [21] |
IFNG KC_DOWN | 332 | −0.25 | −1.23 | 0.050 | 0.128 | ||
IL17&TNF KC UP | 31 | 0.87 | 2.82 | 0.000 | 0.000 | [22] | |
IL1 KC_UP | 48 | 0.75 | 2.68 | 0.000 | 0.000 | [23] | |
TERMINAL DIFFERENTIATION | 33 | 0.58 | 1.86 | 0.000 | 0.001 | [24] | |
PS_INFLAMM DCS_UP | 131 | 0.33 | 1.41 | 0.008 | 0.041 | [18] |
Size, number of genes in gene set.
ES, enrichment score.
NES, normalized enrichment score.
CS, connectivity score.
REF, reference for gene set.