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| Experiment 1 | acquisition | admin | test | |
| run | 1–4 | (30′) | 5 | |
| RMF (n = 13) | rmf | veh | x | |
| RMF+ZIP (n = 5) | rmf | ZIP | x | |
| Saline (n = 9) | sal | veh | x |
rmf: remifentanil, veh: vehicle, sal: saline, admin: administration, reacq: reaquisition, reinst: reinstatement, stau: staurosporine, zips: zip scramble, x: trials without drug reinforcement, ↓: intraaccumbens injection, rmf(1): self-administration of remifentanil only after completion of the first run.
