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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Mol Cancer Ther. 2011 Dec 1;11(2):267–276. doi: 10.1158/1535-7163.MCT-11-0584

Figure 2. RA-mediated FGF8f secretion by differentiating U2OS cells inhibits proliferation and induces differentiation of different subtypes of leukemic myeloblasts at the paracrine level.

Figure 2

(A) Proliferation analysis of HL60 (left) and HL60R (right) cells co-cultured with U2OS cells expressing RARαS77A or FGF8f. (B) Proliferation analysis of HL60 (left) and NB4 (right) cells cultured with different OCM. (C) Granulocytic morphologic differentiation of HL60 cells. (D) Flow cytometric analysis of the expression of CD11b. The corresponding isotypes as well as CD34 antibodies were used as controls.