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A) Chemical structures of PF-2341066 and PF-573228. B) HGF induces the activation of FAK and Pyk2 in medulloblastoma cells in a time-dependent manner Immunoblots showing the time-dependent phosphorylation of FAK and Pyk2 on various tyrosines (Tyr) and serines (Ser) in medulloblastoma cells treated 20 ng/ml HGF for 5 min - 6 hours. The blots were stripped and hybridized for β-Actin as a loading control.
