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. Author manuscript; available in PMC: 2013 Feb 1.
Published in final edited form as: Mol Cancer Ther. 2011 Dec 21;11(2):288–297. doi: 10.1158/1535-7163.MCT-11-0490

Figure 5. Combined inhibition of FAK and c-Met by small molecule kinase inhibitors inhibits medulloblastoma cell invasion more than single inhibitions.

Figure 5

DAOY-HGF cells were treated with either 1 μM FAKi, 100 nM METi, a combination of both, or control for 24 hours. The cells were assessed for invasion using a transwell assay. Cells that invaded through the membrane after 6 hours were fixed and stained with crystal violet. The wells were photographed at 40X magnification and five random fields were quantified. The results show that combined inhibition of FAK and c-Met has greater inhibitory effects on medulloblastoma cell invasion than single inhibitions. A) Representative invasion assay. B) Quantification of invasion assay. * =p< 0.05.