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Dose-dependent DMR signals induced by P2Y agonists. (a) ATP; (b) 2-MeSATP; (c) UTP; (d) ATPγS; (e, f ) the P-DMR amplitudes of P2Y agonists as a function of agonist concentration. HEK293 cells were confluent on the TCT biosensor plate at the time of assays. The data presented are means±SEM of four replicate wells (n=4). 2MeSATP, 2-methylthio-ATP; DMR, dynamic mass redistribution; P2Y, purinergic 2Y; P-DMR; positive DMR; TCT, tissue culture-treated; UTP, uridine triphosphate.
