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The costimulation DMR signals, in comparison with the DMR induced by individual agonist. (a) The DMR induced by 2-MeSATP, ADP, and 2-MeSATP+ADP; (b) the DMR induced by 2-MeSATP, UTP, and 2-MeSATP+UTP; (c) the DMR induced by 2-MeSATP, UDP, and 2-MeSATP+UDP; and (d) the DMR induced by 2-MeSATP, ATPγS, and 2-MeSATP+APTγS. The concentration was 2, 2, 16, 100, and 16 μM for 2-MeSATP, ADP, UTP, UDP, and ATPγS, respectively. Data presented are means±SEM of eight replicate wells (n=8).
